|Species/Subspecies:||Mycoplasma mycoides subsp. mycoides|
|Category:||Notifiable diseases and bacteria|
|Etymology:||Genus name: fungus shaped.|
Species epithet: similar to fungi.
Subspecies epithet: see Species epithet.
|Significance:||CBPP utrotades i de flesta europeiska länder runt år 1900, men sporadiska urbrott har förekommit i framför allt Italien, Portugal och Spanien. Det sista utbrottet rapporterades 1999 från Portugal. Sjukdomen medför idag mycket stora ekonomiska och sociala problem i Afrika.
|Type Strain:||PG1 = NCTC 10114.|
||Forms small and very typical umbonated colonies ("fried egg appearance"), which can be observed in a microscope.|
|Micromorphology:||Very small and pleomorphic. Nonmotile.|
|Gram +/Gram -:||G-, but is normally not gram stained because the cells will then be fragmented.|
|Spec. Char.:||Lacks a cell wall.|
|Disease:||Contagious bovine pleuropneumonia (CBPP).
|Hosts:||Cattle, water buffalo and yak.|
|Clinical Picture:||Elevated body temperature, passivity, ruminating ceases, coughing, difficulty in breathing, hunched back and wasting etc.|
|Virulence Factors:||Adhesion proteins, which make it possible for these bacteria to adhere to the host cell and the enzyme L-alpha-glycerophosphate oxidase, which makes it possible for these bacteria to transfer hydrogen peroxide (H2O2) into the host cell. The host cells will then die. Thus, in the presence of oxygen, hydrogen peroxide is formed when the enzyme converts glycerol-3-phosphate to glycerone phosphate.|
|16S rRNA Seq.:|
||Seven species have been described within the revised genus Mycoplasma to which Mycoplasma mycoides subsp. mycoides belongs. Two of these species are divided into four subspecies. These species and subspecies belong to the so-called the mycoides group and they are closely related to mollicutes within the genus Spiroplasma. This genus contains many plant pathogens. See the phylogenetic tree (Fig. 38:2). Note that it is only for the mollicutes of the mycoides group that the letter M stands for Mycoplasma. For the other species, M means Mesoplasma, Metaplasma, Mycoplasmoides or Mycoplasmopsis.|
|Legislation:||CCPP is included in OIE's A-list of major animal diseases. The disease is in Sweden notifyable to the Swedish Board of Agriculture.|
|Comment:||Based on whole genome sequencing, the taxonomy of mycoplasmas has recently undergone a comprehensive revision. The new taxonomy is about to be introduced in VetBact, but for some mycoplasmas the names have not changed and this applies to members of the mycoides group. Read more about the revised taxonomy of the mollicutes under the Term list of VetBact and see also reference 164 below.|
|Link:||Epiwebb - om epizootisjukdomar [in Swedish]|
|The revised taxonomy of the mollicutes|
The revised taxonomy of mollicutes (mycoplasmas) has now been introduced on VetBact, which means that many of the species have been given new genus names or moved to another higher taxon.Published 2021-11-25. Read more...