|Etymology:||Genus name: rod shaped (bacterium) in ungulates. |
Species epithet: full of knots (refers to the shape of the cells).
|Significance:||The disease causes economic losses and animal suffering in large parts of the world.
|Alternative Species Name(s):||Bacteroides nodosus|
|Type Strain:||ATCC 25549 = CCUG 27824.|
||Small (0.5-3.0 mm in diameter) translucent grayish white colonies after 3-7 days. Grows slowly and the colonies are difficult to see. Gives no hemolysis on FAA plates.|
||Straight or curved rods (1-1.7 x 3-6 µm) with rounded and enlarged ends. Has twitching motility by means of type IV pili.|
|Gram +/Gram -:||G-|
|Other Enzymes:||DNase -, esculinase -, ornithine decarboxylase +, tryptophanase (indole) -, urease -.|
|Biochemical Tests:||H2S +|
|Fermentation of carbohydrates:||D. nodosus does not ferment carbohydrates.|
|Special Media:||Hoof agar is often used for isolation of D. nodosus.|
|Disease:||Footrot. One usually distinguish between benign (mild) and virulent (severe) footrot depending on how severe the symptoms are. These two disease conditions are also referred to as interdigital dermatitis (ID) and under-running footrot, respectively.
|Hosts:||Sheep, goat, cattle|
|Clinical Picture:||Lameness and reduced productivity due to inflammation of the epidermis in the hoof tissue.|
|Virulence Factors:||Type IV pili (fimbriae) which give the bacteria motility in damaged tissue. Extracellular serine protease which makes it possible for the bacterium to digest the tissue of the host animal to get access to free amino acids.|
|Diagnostics:||Gram staining of clinical material, microscopy, culture and confirmation by PCR or MALDI-TOF MS. Benign strains can be differentiated from virulent ones by PCR.|
|16S rRNA Seq.:|
||Only one species has been described within genus Dichelobacter and this species is related to species within genus Stenotrophomonas.|
|Reference(s):||No. 2, 39, 127|
|The revised taxonomy of the mollicutes|
The revised taxonomy of mollicutes (mycoplasmas) has now been introduced on VetBact, which means that many of the species have been given new genus names or moved to another higher taxon.Published 2021-11-25. Read more...